Pharmaceutical

DL-4-Chlorophenylalanine

  • Chemical Name: DL-4-Chlorophenylalanine
  • CAS: 7424-00-2
  • Purity: 99%
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1.What is the DL-4-Chlorophenylalanine ?

4-Chloro-DL-phenylalanine has been used:as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras+ male zebrafishto induce insomnia in rat modelsused to treat embryos to examine its effect on serotoninfor the selection of Enterococcus faecalis transformants with pESentA32 plasmidto feed flies to explore serotonin effect

p-chlorophenylalanine
14173-39-8,1991-78-2

p-chlorophenylalanine

DL-Phe(4Cl)
7424-00-2,1991-78-2

DL-Phe(4Cl)

Conditions
Conditions Yield
With Pseudomonas putida phenylalanine racemase; Enzymatic reaction;
With C16H11ClCuN2O5; sodium hydroxide; In water; at 30 ℃; for 13h; Time;
ethyl 3-(4-chlorophenyl)-2-(hydroxyimino)propionate
1353886-55-1

ethyl 3-(4-chlorophenyl)-2-(hydroxyimino)propionate

DL-Phe(4Cl)
7424-00-2,1991-78-2

DL-Phe(4Cl)

Conditions
Conditions Yield
With sodium tetrahydroborate; water; nickel; sodium hydroxide; In methanol; at 20 - 30 ℃;
90%
ethyl 3-(4-chlorophenyl)-2-(hydroxyimino)propionate; In methanol; at 20 ℃;
With sodium tetrahydroborate; water; sodium hydroxide; In methanol; at 50 - 64 ℃;

2.What is the CAS number for DL-4-Chlorophenylalanine ?

The CAS number of DL-4-Chlorophenylalanine is 7424-00-2.

More information of DL-4-Chlorophenylalanine 7424-00-2 are:

CAS?Number

7424-00-2

Density

1.336 g/cm3

Melting Point

>240 °C (dec.)(lit.)

Boiling Point

339.5 °C at 760 mmHg

Flash Point

159.1 °C

Refractive Index

1.5790 (estimate)

HS CODE

29224985

PSA

63.32000

LogP

1.99470

Pka

pK1: 2.08(+1);pK2: 8.96(0) (25°C)

3.What are another words for DL-4-Chlorophenylalanine ?

Synonyms?for?DL-4-Chlorophenylalanine 7424-00-2:Alanine,3-(p-chlorophenyl)-, DL- (8CI);DL-Phenylalanine, 4-chloro-;3-(p-Chlorophenyl)alanine;4-Chloro-DL-phenylalanine;4-Chlorophenylalanine;CP10188;DL-3-(p-Chlorophenyl)alanine;DL-p-Chlorophenylalanine;Fenchlonine;Fenclonin;Fenclonine;NSC 77370;p-Chloro-DL-phenylalanine;p-Chlorophenylalanine;1991-78-2;

4.What is the molecular formula of DL-4-Chlorophenylalanine?

The chemical formula of ?DL-4-Chlorophenylalanine is?C9H10ClNO2 which containing 9 Carbon atoms,10 Hydrogen atoms,1 Chlorine atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??DL-4-Chlorophenylalanine?is 199.637.

5.What is DL-4-Chlorophenylalanine (7424-00-2) used for?

DL-4-Chlorophenylalanine, also known as 4-Chloro-DL-phenylalanine, is an amino acid analog that acts as an irreversible tryptophan hydroxylase inhibitor. It is structurally similar to the natural amino acid L-phenylalanine, with a chlorine atom replacing one of the hydrogen atoms on the phenyl ring. This modification results in the inhibition of tryptophan hydroxylase, an enzyme responsible for the conversion of tryptophan to serotonin, thereby depleting serotonin levels in the brain.

InChI:InChI=1/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

Relevant articles related to DL-4-Chlorophenylalanine:

Article

Source

Organocatalytic Enantioselective Addition of α-Aminoalkyl Radicals to Isoquinolines

Liu, Xiangyuan,Liu, Yang,Chai, Guobi,Qiao, Baokun,Zhao, Xiaowei,Jiang, Zhiyong

supporting information, p. 6298 - 6301 (2018/10/09)

Phenylalanine ammonia lyase catalyzed synthesis of amino acids by an MIO-cofactor independent pathway

Lovelock, Sarah L.,Lloyd, Richard C.,Turner, Nicholas J.

supporting information, p. 4652 - 4656 (2014/05/20)

6.Buy DL-4-Chlorophenylalanine with the best price .

Duphate Biologychemical Technology Co., Limited is a quality supplier of DL-4-Chlorophenylalanine. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on DL-4-Chlorophenylalanine 7424-00-2.

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