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BPOC REAGENT

  • Chemical Name: BPOC REAGENT
  • CAS: 31140-37-1
  • Purity: 99%
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Cost-effective and customizable BPOC REAGENT 31140-37-1 supplier

  • Molecular Formula: C24H22 O5
  • Molecular Weight: 390.436
  • Vapor Pressure: 2.4E-11mmHg at 25°C 
  • Melting Point: 90-100oC (dec.) 
  • Boiling Point: 530.7°Cat760mmHg 
  • Flash Point: 230.1°C 
  • PSA: 61.83000 
  • Density: 1.178g/cm3 
  • LogP: 5.59090 

BPOC REAGENT(Cas 31140-37-1) Usage

General Description

BPOC (2-bromo-1-hydroxy-7-benzyloxy-2, 3-dihydro-1H-inden-4-one) Reagent is a chemical used in the synthesis of peptides and other organic compounds. It is a brominated derivative of 7-hydroxy-1H-inden-4-one and is commonly used as a reagent for protecting the hydroxyl group of serine and threonine residues during peptide synthesis. BPOC reagent reacts with the hydroxyl group to form a stable benzyl ether, effectively blocking the group from participating in unwanted reactions during peptide assembly. It is an essential tool for the solid-phase peptide synthesis and is widely used in research laboratories and pharmaceutical industries for the production of peptide-based drugs and therapeutic agents.

InChI:InChI=1/C24H22O5/c1-24(2,20-13-9-18(10-14-20)17-7-5-4-6-8-17)29-23(26)28-21-15-11-19(12-16-21)22(25)27-3/h4-16H,1-3H3

31140-37-1 Process route

methyl 4-hydroxylbenzoate
99-76-3,156291-94-0

methyl 4-hydroxylbenzoate

methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate
31140-37-1

methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: benzene
2: Py / CH2 Cl2
With pyridine; In dichloromethane; benzene;
2-biphenyl-4-yl-propan-2-ol
34352-74-4

2-biphenyl-4-yl-propan-2-ol

methyl 4-[(chlorocarbonyl)oxy]benzoate
31140-40-6

methyl 4-[(chlorocarbonyl)oxy]benzoate

methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate
31140-37-1

methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate

Conditions
Conditions Yield
With pyridine; In dichloromethane;

31140-37-1 Upstream products

  • 34352-74-4
    34352-74-4

    2-biphenyl-4-yl-propan-2-ol

  • 31140-40-6
    31140-40-6

    methyl 4-[(chlorocarbonyl)oxy]benzoate

  • 99-76-3
    99-76-3

    methyl 4-hydroxylbenzoate

31140-37-1 Downstream products

  • 210546-16-0
    210546-16-0

    [2-(3,5-Dibromo-4-hydroxy-phenyl)-ethyl]-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester

  • 605674-86-0
    605674-86-0

    (S)-2-(1-Biphenyl-4-yl-1-methyl-ethoxycarbonylamino)-6-[(2,4-dimethoxy-benzyloxy)-(2-nitro-benzenesulfonyl)-amino]-hexanoic acid

  • 210546-18-2
    210546-18-2

    {2-[4-(3-Amino-propoxy)-3,5-dibromo-phenyl]-ethyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester

  • 210546-19-3
    210546-19-3

    (2-{3,5-Dibromo-4-[3-(cyanocarbonyl-amino)-propoxy]-phenyl}-ethyl)-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester

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