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Cost-effective and customizable BPOC REAGENT 31140-37-1 supplier
- Molecular Formula: C24H22 O5
- Molecular Weight: 390.436
- Vapor Pressure: 2.4E-11mmHg at 25°C
- Melting Point: 90-100oC (dec.)
- Boiling Point: 530.7°Cat760mmHg
- Flash Point: 230.1°C
- PSA: 61.83000
- Density: 1.178g/cm3
- LogP: 5.59090
BPOC REAGENT(Cas 31140-37-1) Usage
|
General Description |
BPOC (2-bromo-1-hydroxy-7-benzyloxy-2, 3-dihydro-1H-inden-4-one) Reagent is a chemical used in the synthesis of peptides and other organic compounds. It is a brominated derivative of 7-hydroxy-1H-inden-4-one and is commonly used as a reagent for protecting the hydroxyl group of serine and threonine residues during peptide synthesis. BPOC reagent reacts with the hydroxyl group to form a stable benzyl ether, effectively blocking the group from participating in unwanted reactions during peptide assembly. It is an essential tool for the solid-phase peptide synthesis and is widely used in research laboratories and pharmaceutical industries for the production of peptide-based drugs and therapeutic agents. |
InChI:InChI=1/C24H22O5/c1-24(2,20-13-9-18(10-14-20)17-7-5-4-6-8-17)29-23(26)28-21-15-11-19(12-16-21)22(25)27-3/h4-16H,1-3H3
31140-37-1 Process route
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-
99-76-3,156291-94-0
methyl 4-hydroxylbenzoate
-
-
31140-37-1
methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: benzene
2: Py / CH2
Cl2
With
pyridine;
In
dichloromethane; benzene;
|
-
-
34352-74-4
2-biphenyl-4-yl-propan-2-ol
-
-
31140-40-6
methyl 4-[(chlorocarbonyl)oxy]benzoate
-
-
31140-37-1
methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate
| Conditions | Yield |
|---|---|
|
With
pyridine;
In
dichloromethane;
|
31140-37-1 Upstream products
-
34352-74-4
2-biphenyl-4-yl-propan-2-ol
-
31140-40-6
methyl 4-[(chlorocarbonyl)oxy]benzoate
-
99-76-3
methyl 4-hydroxylbenzoate
31140-37-1 Downstream products
-
210546-16-0
[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethyl]-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester
-
605674-86-0
(S)-2-(1-Biphenyl-4-yl-1-methyl-ethoxycarbonylamino)-6-[(2,4-dimethoxy-benzyloxy)-(2-nitro-benzenesulfonyl)-amino]-hexanoic acid
-
210546-18-2
{2-[4-(3-Amino-propoxy)-3,5-dibromo-phenyl]-ethyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester
-
210546-19-3
(2-{3,5-Dibromo-4-[3-(cyanocarbonyl-amino)-propoxy]-phenyl}-ethyl)-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester