DOBUTAMINE HYDROCHLORIDE

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1.What is the DOBUTAMINE HYDROCHLORIDE ?

Dobutamine hydrochloride occurs as a white to off-white crystalline powder, which is sparingly soluble in water and in alcohol. Dobutamine has a pKa of 9.4.

ChEBI: The hydrochloride salt of dobutamine. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used to increase the contractility of the heart in the m nagement of acute heart failure.

Dobutamine hydrochloride, a dopamine derivative, is a selective β1-adrenergic agonist. It is a sympathomimetic agent with inotropic action (changes strength of muscle contraction) on the heart. However, it may have some α and β2-agonist properties as well.The active substance strengthens the contraction power of the heart, increases the stroke volume and thus the blood circulation of the organs. It is used for the treatment of acute heart failure and for cardiac stress tests.

2.What is the CAS number for DOBUTAMINE HYDROCHLORIDE ?

The CAS number of DOBUTAMINE HYDROCHLORIDE is 49745-95-1.

3.What are another words for DOBUTAMINE HYDROCHLORIDE ?

Synonyms?for?DOBUTAMINE HYDROCHLORIDE 49745-95-1:1,2-Benzenediol,4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (9CI);DL-Dobutamine hydrochloride;Dobutrex;Inotrex;NSC299583;

4.What is DOBUTAMINE HYDROCHLORIDE (49745-95-1) used for?

Dobutamine hydrochloride is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo. It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions. As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects. It is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 ?M.

InChI:InChI=1/C6H6O2.ClH/c7-5-3-1-2-4-6(5)8;/h1-4,7-8H;1H

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